Blebbistatin molecular weight
WebBlebbistatin was discovered in 2003 and exhibits high affinity and selectivity for myosin-2. 167 Myosins from classes-1, -5, -10, but also smooth muscle myosin-2, are weakly or not … Web(-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases (Kovács et al.; Straight et al.). It rapidly and reversibly inhibits Mg-ATPase activity and in …
Blebbistatin molecular weight
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WebBlebbistatin potently inhibits several striated muscle myosins as well as vertebrate nonmuscle myosin IIA and IIB with IC 50 values ranging from 0.5 to 5 μM. Smooth muscle myosin is only poorly inhibited (IC 50 =80 … WebBlebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier …
WebBLEBBISTATIN, (-)- 8WII7624I5 Other Structure Moieties 1: General Activity Publications Application Record Details Names 4: Identifiers 7: BLEBBISTATIN, (-)- 8WII7624I5 ... Molecular Weight: 292.3318: Charge: 0: WebMolecular Formula. C 18 H 16 N 2 O 2. Formula Weight. 292.3. Purity. ≥98%. Formulation(Request formulation change) A crystalline solid. ... (–)-Blebbistatin is a …
WebMolecular Formula. C 17 H 13 N 3 O 4. Formula Weight. 323.3. Purity. ≥98%. Formulation(Request formulation change) A crystalline solid. ... -Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC 50 s = 0.5-5 µM), while poorly inhibiting smooth muscle ... WebBlebbistatin Molecular formula C 18 H 16 N 2 O 2 Molecular weight 292.34 Percent composition C 73.95%, H 5.52%, N 9.58%, O 10.95%
WebJan 5, 2024 · Blebbistatin is a potent and selective myosin II inhibitor with IC50s ranging from 0.5 to 5 μM. Blebbistatin potently inhibits several striated muscle myosins as well …
WebCAS: 674289-55-5: Molecular Formula: C18H16N2O2: Molecular Weight (g/mol) 292.338: InChI Key: LZAXPYOBKSJSEX-UHFFFAOYSA-N: Synonym +/--blebbistatin, … roofers auburn maineWebThe following data is based on the product molecular weight 292.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions. roofers aughtonWebFind blebbistatin and related products for scientific research at MilliporeSigma. US EN. Applications Products Services Support. Advanced Search. Structure Search. ... roofers austin mnWebSource: Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. roofers auburn waWebMar 6, 2005 · Molecular motors play a central role in cytoskeletal-mediated cellular processes and thus present an excellent target for cellular control by pharmacological agents. Yet very few such compounds ... roofers austin arWebSelective inhibitor of myosin II ATPase activity. Inactive enantiomer of (±)-blebbistatin (Cat. No. 1760) Shop (R)-(+)-Blebbistatin, Tocris Bioscience™ at Fishersci.com Fisher Scientific ... Molecular Formula: … roofers auburnWebBlebbistatin is a myosin inhibitor mostly specific for myosin II. [1] [2] It is widely used in research to inhibit heart muscle myosin, non-muscle myosin II , and skeletal muscle myosin. Blebbistatin has been especially useful in optical mapping of the heart, [3] and its recent use in cardiac muscle cell cultures has improved cell survival time. roofers auckland