Clarithromycin interaction with simvastatin
WebDec 11, 2014 · The changes include contraindications to concomitant use with certain medicines and maximum dose recommendations when simvastatin is taken with a … WebSimvastatin tablets USP are an HMG-CoA reductase inhibitor indicated: ()To reduce the risk of total mortality by reducing risk of coronary heart disease death, non-fatal myocardial infarction and stroke, and the need for coronary and non-coronary revascularization procedures in adults with established coronary heart disease, cerebrovascular disease, …
Clarithromycin interaction with simvastatin
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WebApr 1, 2024 · Descriptions. Clarithromycin is used to treat bacterial infections in many different parts of the body. It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. This medicine is also used to prevent and treat Mycobacterium avium complex (MAC) infection. Clarithromycin belongs to the class of … WebJun 9, 2016 · If you're taking a statin and are 65 or older, steering clear of the antibiotics Biaxin (clarithromycin) and erythromycin can help keep you safe from some uncommon — but potentially life ...
WebAug 17, 2024 · Clarithromycin has minor interactions with at least 98 different drugs. This information does not contain all possible interactions or adverse effects. ... (statins) that are extensively metabolized by CYP3A4 (lovastatin, simvastatin), due to the increased risk of muscle disease (myopathy), including destruction of muscle tissue (rhabdomyolysis ... WebApr 1, 2024 · Clarithromycin may increase the risk for heart and blood vessel problems in patients with these conditions. It may occur a year or 10 years after the use of this …
WebDec 23, 2014 · They found that the co-prescription of clarithromycin and a statin was linked to an increased rate of mortality and hospital … WebJun 6, 2024 · Dose adjustments are necessary with simvastatin when taken concomitantly with certain pharmacotherapy. Adjustments in simvastatin strength reduce potential statin-associated toxicities, …
WebClarithromycin is known as a macrolide antibiotic. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (such as ...
WebDiscussion: Clarithromycin is a potent inhibitor of CYP3A4, the major enzyme responsible for simvastatin metabolism. The concomitant administration of macrolide … pacemaker and chainsaw useWebApr 1, 2024 · Descriptions. Simvastatin is used together with a proper diet to treat high cholesterol and triglyceride (fat) levels in the blood. This medicine may help prevent medical problems (eg, heart or blood vessel problems, heart attacks, or strokes) caused by clogged blood vessels. Simvastatin may also be used to prevent certain types of heart ... pacemaker and defibrillator differenceWebQuetiapine — concurrent use is contraindicated. If necessary, monitor for adverse effects. Sildenafil, tadalafil — dose reductions may be necessary. Statins — concurrent administration with clarithromycin increases their plasma levels and the risk of myopathy. Lovastatin, simvastatin — concurrent use is contraindicated. pacemaker and defibrillator comboWebFeb 5, 2024 · Certain drugs can interact with atorvastatin (Lipitor) and increase its side effects. These include fibrates, niacin supplements, cyclosporine, clarithromycin, itraconazole, HIV protease inhibitors, oral … pacemaker and defibrillator icd 10WebApr 27, 2024 · An event is serious (based on the ICH definition) when the patient outcome is:Drug interaction. An 81-year-old man developed rhabdomyolysis and drug-induced liver injury (DILI) following concomitant administration of simvastatin and clarithromycin. The man was admitted to the ED due to asthenia, muscle weakness … pacemaker and defibrillator during deathWebWhat key adverse effects are associated with clarithromycin? Gastrointestinal — diarrhoea, vomiting, dyspepsia, nausea, abdominal pain (common), taste disturbance. … jennison investor relationsWebApr 27, 2024 · An 81-year-old man developed rhabdomyolysis and drug-induced liver injury (DILI) following concomitant administration of simvastatin and clarithromycin. The man … pacemaker and dental prophylaxis