Cx43 antibody
WebJan 24, 2013 · The Cx43 antibody recognizes three bands by Western blots, which consists of a nonphosphorylated form (P0) at 41 kDa and two phosphorylated forms (P1, P2), ranging in size between 43 and 45 kDa. As shown in Figure 4A , AGE upregulated total Cx43 protein expression, including P0, P1 and P2, whereas BSA alone showed no significant effect. WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity …
Cx43 antibody
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WebConnexin-43 (Cx43, also known as gap junction alpha-1), a member of connexin family, plays essential roles in gap junction communication that … WebConnexin-43 is a multi-pass membrane protein and is the most ubiquitous connexin with widespread tissue expression pattern. Connexin-43 can be phosphorylated at multiple sites and phosphorylation is shown to regulate the kinetics of its trafficking, assembly, gating and turnover in a cell-cycle-stage specific manner.
WebReactivity: Rat (QC Testing), Human, Mouse, Dog, Chicken (Tested in Development) Isotype: Mouse IgG1. Immunogen: Rat Connexin-43 aa. 252-270. Application: Western … WebSpecificity. Anti-Connexin 43 reacts specifically with connexin 43. By immunoblotting, the antibody detects a single band or 2-3 bands at 43 kDa region. Staining of connexin 43 …
WebRb X Ms Connexin 43 (Cx43) Antibody, C-terminus Anti-Connexin 43 Antibody, C-terminus, cytosolic is an antibody against Connexin 43 for use in ELISA, IF, IH, IP & WB. - Find MSDS or SDS, a COA, data sheets and more information. WebBrowse all Antibodies Recent searches: CX43 Custom Antibody Service Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications. More than 18,000 custom antibodies created so far. Talk to a specialist now Performance Guarantee
WebConnexin 43 (Cx43) is a member of the large family of gap junction proteins. Connexins assemble as a hexamer and are transported to the plasma membrane to create a …
WebApr 5, 2024 · 3 SUMO ligase for its target proteins. However, whether Cx43 is a target protein of PIASy and whether Cx43 SUMOylation plays a role in I/R-induced arrhythmias are largely unknown. Methods: Male Sprague–Dawley rats were infected with PIASy short hairpin RNA (shRNA) using recombinant adeno-associated virus subtype 9 (rAAV9). Two … gutter cleaning scarisbrickWebWestern blot of anti-Connexin 43, 247-382 antibody (clone 2F5), and isotype-matched IgG1 control. Lane 1: 20 µg of human brain lysate; Lane 2: 20 µg of Mouse brain lysate. ... So far, 21 Connexins have been discovered in humans. The gene GJA1 encodes Connexin 43 (Cx43), which is the most expressed Connexin, and can be found in many human ... gutter cleaning saffron waldenWebNov 20, 2006 · For panel C, samples from the same cell lines were tested for immunoreactivity to a monoclonal anti–Cx43-NT antibody. Panel D is an immunoblot of rat heart, brain and ovary extracts probed using the polyclonal anti–Cx43-CT antibody. Note the 20-kDa band present in the extracts of NRK, AT84 and bEnd3 cells. boxwood seattleWebDescription. The antibody is a mouse monoclonal antibody raised against CX43. It has been selected for its ability to recognize CX43 in immunohistochemical staining and western blotting. Species Reactivity. Human. Clonality. Monoclonal. Host Species. Mouse. gutter cleaning sandusky ohioWebMay 31, 2024 · We found that Cx43 promoted the release of ATP from injured TECs, which in turn induces the pyroptosis of macrophages surrounding these epithelial cells, thus activating an inflammatory reaction... boxwoods costWebApr 20, 2024 · a, b The SCs of P1 pups with the indicated Cx43 genotype were cross-sectioned, double immunostained with anti-Cx43 and anti-ARL13B antibodies (a) or anti-Phospho-Cx43 (Ser386) antibody (b), and ... gutter cleaning scarborough ukWebMay 27, 2024 · Connexin 43 (Cx43) is the predominant connexin subtype expressed in osteocytes. Osteocytes, accounting for 90%–95% of total bone cells, function as orchestrators coordinating balanced activity between bone-resorbing osteoclasts and bone-forming osteoblasts. In this study, two newly developed osteocytic cell lines, OCY454 … gutter cleaning se portland