WebAbstract. Exposure of mice to a diet containing 3,5-diethoxycarbonyl-1, 4-dihydrocollidine (DDC) induces porphyrin accumulation, cholestasis, immune response, and hepatobiliary … WebAug 28, 2024 · They were fed the SAFE A04 diet (SAFE™) containing 0.089% (in weight) of 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC, Sigma-Aldrich) for 2 weeks (from day 0 to 14). After one week of recovery with the regular diet, mice were fed again with the DDC-supplemented diet for one more week. For bulk mRNA-sequecing, 4 healthy/normal …
3,5-Diethoxycarbonyl-1,4-Dihydrocollidine Diet: A …
WebXenobiotics and drugs may lead to cholangiopathies and biliary fibrosis, but the underlying mechanisms are largely unknown. Therefore, we aimed to characterize the cause and consequences of hepatobiliary injury and biliary fibrosis in 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)-fed mice as a novel model of xenobiotic-induced cholangiopathy. WebOct 1, 2024 · This study focused on the preventive effects of the extracts of Rhus chinensis Mill. (RCM) fruits on cholestasis induced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine … the north face hyvent jacket
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WebMar 4, 2024 · We performed experiments with C57BL/6 J mice treated with 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) and melatonin to verify the role of melatonin in the mouse model of cholestasis. Primary mouse hepatocytes were used for in vitro studies to study the mechanisms of action of melatonin in cholestasis. The levels of … http://www.zhbybio.com/newsinfoen/4612.html?page=5 WebOct 1, 1974 · 3,5-Diethoxycarbonyl-1,4-dihydrocollidine (DDC) is a porphyrinogenic agent and is a powerful inducer of δ-aminolaevulinate synthetase, the first and rate … the north face hyvent fleece lined