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Gata2 transcription factor

WebGATA-binding factor 1 or GATA-1 (also termed Erythroid transcription factor) is the founding member of the GATA family of transcription factors. This protein is widely expressed throughout vertebrate species. In humans and mice, it is encoded by the GATA1 and Gata1 genes, respectively. These genes are located on the X chromosome in both … WebGATA2 (located at 3q21.3) is an early hematopoietic transcription factor most active in myeloid development. 47 The syndrome of monocytopenia and mycobacterial disease …

GATA2 - an overview ScienceDirect Topics

WebMar 21, 2024 · GATA2 is a transcription factor involved in stem cell maintenance with key roles in hematopoietic development. GATA2 mutations are associated with a variety of inherited and acquired … WebApr 13, 2024 · GATA-1-mediated replacement of GATA-2 represses Gata2 transcription during erythroid maturation via FOG-1- and SetD8-dependent mechanisms. 65 GATA switching occurs at 5 highly conserved Gata2 sites, −77, −3.9, −2.8, −1.8, and +9.5 kb relative to the 1S promoter. 28, 56, 57, 64 As GATA-2 and GATA-1 occupy these sites at … tatra utca sobarlang https://jfmagic.com

GATA family transcriptional factors: emerging suspects in …

WebJun 1, 2006 · Here, we report several lines of data supporting the involvement of GATA2,a transcription factor that contains two C4 zinc fingers, in such crosstalk. GATA2 was … WebThe gene promoter is a complex area containing numerous binding sites for transcription factors, which determines the transcription start site and frequency [25]. ... SP1, GATA2, NFIC, and other transcription factor-binding sites. MZF1, a member of the C2H2-type zinc finger protein family, is involved in the proliferation and differentiation of ... WebJan 21, 2024 · Our studies reveal that GATA2 promotes robust gene transcription to maintain mast cell identity and respond to antigenic stimulation by binding to super-enhancer regions with dense GATA2... 4k基地

The transcription factor complex LMO2/TAL1 regulates branching …

Category:Genome-Wide Characterization and Expression Analysis of GATA ...

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Gata2 transcription factor

GATA2 deficiency - Wikipedia

WebThe GATA2 transcription factor contains two zinc finger (i.e. ZnF) motifs. C-ZnF is located toward the protein's C-terminus and is responsible for binding to specific DNA sites. N-ZnF is located toward the proteins N-terminus and is responsible for interacting with various other nuclear proteins that regulate its activity. WebApr 13, 2024 · The GATA transcription factor family Mammalian genomes encode six structurally related members of the GATA family, which function as tissue-specific master …

Gata2 transcription factor

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WebMay 4, 2024 · Vascular endothelial growth factor (VEGF)-A is a major proangiogenic chemoattractant and mitogen that is secreted from hypoxic sites and that binds to VEGF … WebMay 4, 2024 · Plant transcription factors are usually regarded as molecular switches for regulating gene expression, which play vital role in plant growth, development, as well as the response to diverse stresses. ... Chiba T., Feldman L.J. Longitudinal patterning in roots: A GATA2–auxin interaction underlies and maintains the root transition domain ...

Web该GATA2 Polyclonal Antibody. This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of … WebGATA2 (located at 3q21.3) is an early hematopoietic transcription factor most active in myeloid development. 47 The syndrome of monocytopenia and mycobacterial disease (monoMAC) is characterized by late childhood or adult-onset disseminated nontuberculous mycobacterial disease or disseminated fungal disease.

WebGATA1 and GATA2 are expressed principally in hematopoietic lineages, and have essential roles in the development of multiple hematopoietic cells, including erythrocytes and … WebApr 19, 2005 · GATA2 transcription factor is an inhibitor of adipogenesis and an activator of vascular cells. We hypothesized that GATA2 activity is controlled by insulin during adipogenesis, linking metabolic homeostasis and inflammation. Methods and Results— We show that insulin induces GATA2 phosphorylation on serine 401 in a PI …

WebSep 22, 2024 · After discovery of the founding member of the GATA transcription factor family GATA1, 1,2 GATA2 was shown by Orkin and colleagues in 1994 to be a vital determinant of multilineage …

WebJan 31, 2024 · The GATA2 variant allele frequency (VAF) in coding mutations was >40% in DNA sequencing (described in the next section), consistent with germline mutations, either de novo or inherited (the exception was patient 100, for whom VAF data were not available). tatra utca 6 budapestWebThe master regulatory transcription factor GATA-2 triggers hematopoietic stem and progenitor cell generation. GATA2 haploinsufficiency is … tatra urlaubWebGATA2 deficiency is a grouping of several disorders caused by common defect, namely, familial or sporadic inactivating mutations in one of the two parental GATA2 genes.Being … tatrawest kameraWeb2 days ago · The early transcription factor GATA-2 is expressed in classical Hodgkin’s lymphoma. The Journal of Pathology, 204(5), 538–545. doi:10.1002/path.1664 … tatra wikipedia enWeb2 days ago · The early transcription factor GATA-2 is expressed in classical Hodgkin’s lymphoma. The Journal of Pathology, 204(5), 538–545. doi:10.1002/path.1664 10.1002/path.1664 4k 哈利波特WebMay 15, 1997 · The zinc-finger transcription factor GATA-2 plays a critical role in maintaining the pool of early hematopoietic cells. To define its specific functions in the … tatra v570 wikipediaWebGATA2 (located at 3q21.3) is an early hematopoietic transcription factor most active in myeloid development. 47 The syndrome of monocytopenia and mycobacterial disease (monoMAC) is characterized by late childhood or adult-onset disseminated nontuberculous mycobacterial disease or disseminated fungal disease. tatra west kamera