WebOct 22, 2024 · Methods and results: The effects of high-dose vs low-dose losartan on clinical outcomes in patients with heart failure (HEAAL) trial randomized 3834 patients with HFrEF intolerant to angiotensin-converting enzyme inhibitors to losartan 150 mg/d (high dose) vs 50 mg/d (low dose). We studied the associations of serum potassium (baseline … WebMethods: HEAAL was a double-blind trial, comparing the effect of two doses of losartan 150 (high dose) vs. 50 (low dose) mg/day among 3834 patients with symptomatic HF, a left ventricular ejection fraction≤40 %, and known intolerance to angiotensin-converting enzyme inhibitors. In the present study, we studied the associations of SUA with ...
HEAL - Wiki Journal Club
WebFeb 1, 2024 · The effects of high vs low doses of ACE inhibitors or angiotensin receptor blockers on outcomes in heart failure have been examined in 2 major prospective randomized clinical trials: the Assessment of Treatment with Lisinopril and Survival (ATLAS) and the Heart Failure Endpoint Evaluation of Angiotensin II Antagonist Losartan … WebMar 28, 2007 · A post hoc analysis from the ACTIVE-HF trial showed reduced 60-day mortality with tolvaptan treatment initiated within the first 48 hours of hospitalization with worsening HF and severe volume overload. 22 A benefit in mortality and HF-related morbidity was also suggested by a post hoc analysis of the Multicenter Evaluation of … blinking pins wholesale
Multistate Model to Predict Heart Failure Hospitalizations and All ...
WebSep 16, 2024 · Treatment effect of high- vs. low-dose losartan in the HEAAL trial. In HEAAL, men appeared to have benefited more from high-dose (compared with low-dose) losartan, whereas women appeared to have responded similarly to low or high doses. ACH, all-cause hospitalization; ACM, all-cause mortality; CI confidence interval; HR, hazard ratio. WebThe NETWORK trial (Network of General Practitioners and Hospital Physicians Involved in the Study of Low Versus High Doses of Enalapril in ... CHIPS, Captopril in Heart Insufficient Patients Study; HD, high dose; HEAAL, Heart Failure . Circ Heart Fail. 2024;10:e003956. DOI: 10.1161/CIRCHEARTFAILURE.117.003956 August 2024 10. dose of angiotensin ... WebMay 29, 2024 · The HEAAL trial compared low vs. high dose of losartan. We reassessed the efficacy and safety of high- vs. low-dose in men vs. women using Cox models and … blinking ornaments