Hif-1α abcam ab16066
Web(ab16066) Anti-HIF-1 alpha antibody [mgc3] Sign in or register to save this reagent to your favourites Supplier Abcam Host Mouse Type Primary Clonality Monoclonal (mgc3) … Web19 lug 2024 · Liu, H., Zhang, Z., Zhou, S. et al. Claudin-1/4 as directly target gene of HIF-1α can feedback regulating HIF-1α by PI3K-AKT-mTOR and impact the proliferation of …
Hif-1α abcam ab16066
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Web缺氧诱导因子（HIF）是转录因子，能对细胞环境中可用氧的变化做出反应，尤其是对氧气的减少或缺氧做出反应。 HIF-1α 调控着 40 多种基因的转录，包括促红细胞生成素、葡萄糖转运蛋白、糖酵解酶、血管内皮生长因子和其它基因蛋白产物能增加氧输送或促进缺氧新陈代谢。 2024 诺贝尔生理学或医学奖 表明，了解细胞对氧气的反应方式十分重要。 该奖项联 … Web15 lug 2024 · The slides were incubated in primary Ab (RCN3, Abcam, ab204178, 1:200; HIF-1α, Abcam, ab16066, 1:200), followed by treatment with secondary Ab, and a 3,3′-diaminobenzidine staining kit. The IHC intensity for each tissue slide was evaluated independently by two experienced pathologists who were blinded to patients' clinical data.
WebHIF-1α, EGFR, and PHD3 protein expression was assessed by Western blotting. Cell survival was determined in a colony formation assay. PHD3 overexpression suppressed HIF-1α protein expression and EGFR phosphorylation and enhanced the 2 Gy irradiation-mediated reductions in HIF-1α and phosphorylated (p)-EGFR under either normoxic or … WebMouse anti-HIF-1α antibody reacts specifically with HIF1 α subunit of sheep, mouse, rat, ferret and human. Immunogen. peptide corresponding to amino acids 432-528 of the …
WebHIF-1α is known to be active under hypoxic conditions. HIF-1 α status was investigated in A-549 lung, DU-145 prostate and MCF-7 breast cancer cell lines exposed to bile acids … Web6 ott 2024 · HIF-1α is ubiquitous in human and mammalian cells, regulating glycolytic metabolism, angiogenesis and apoptosis in the absence of oxygen . When oxygen partial …
WebUniProt Q16665 · HIF1A_HUMAN Protein Hypoxia-inducible factor 1-alpha Gene HIF1A Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 826 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Align Download Add
WebUnder normoxic conditions, HIF-1 alpha is largely undetectable. Hypoxia needs to be induced in most cells and normal tissues. Location Cytoplasmic in normoxic conditions. … gi doctors nkchfruitland new construction homesWebHIF-1α is an essential transcription factor that mediates hypoxic-adaptive responses in cells and maintains cancer cell clonogenicity in hypoxic conditions. 27, 28 HIF-1α is a downstream factor of the EGFR-mediated signaling pathway, an essential regulatory component of the tumor microenvironment and radioresistance. 12 There exists a … fruitland new mexicoWebThe primary antibodies HIF-1α ( 1:2000 dilution, ab16066; Abcam ,) and HK- II ( 1:5000 dilution, ab227198; Abcam) were diluted and incubated with the membrane December … fruitland near meWeb1 set 2024 · HIF-1α is mainly involved in promoting tumor migration, invasion and metastasis, angiogenesis and other aspects, involving various signaling pathways (Chu … gi doctor spanishWeb23 ago 2024 · ab16066 Product Name : HIF1 alpha antibody [mgc3] Host Species : Mouse Clonality : monoclonal Product Type : Primary antibodies Size : 100 ul SwissProtID : … gi doctors plainfield ilWebAnti-HIF-1 alpha antibody [H1alpha67] (ab1) at 1/400 dilution + Human whole cell lysate (human lung adenocarcinoma cell line ADLC-5M2) treated for 16 hours with 100 … fruitland nm