WebDec 1, 2024 · We further identified STAT3 in our extracted subnetwork and crucial proteins, indicating that several CSC-related proteins, including drug resistance markers (ABCG1, ABCG2, ABCB1, ABCB10, ABCC1,... WebAug 3, 2024 · raised against amino acids 50-240 mapping at the N-terminus of Stat3 of human origin Stat3 Antibody (F-2) is recommended for detection of Stat3 of mouse, rat and human origin by WB, IP, IF, IHC (P) and ELISA; also reactive with additional species, including and equine, bovine and porcine
Role of STAT3 signaling pathway in breast cancer
WebNov 18, 2024 · STAT3/p-STAT3 expression in G1 + G2 was significantly lower than that in G3 (OR = 0.55, 95% CI = 0.40–0.77, p < 0.00001). We obtained consistent outcomes in the ovarian cancer biomarker subgroups (STAT3 and p-STAT3) (STAT3: OR = 0.37, 95% CI = 0.20–0.69, p = 0.002; p-STAT3: OR = 0.65, 95% CI = 0.44–0.97, p = 0.035) (Fig. 6 ). WebAug 1, 2024 · Doxorubicin alone did not decrease p-Akt and p-Stat3 levels. Cucurbitacin D decreased p-NF-κB and p-Stat3 levels. Doxorubicin in combination with cucurbitacin D increased p-p53 levels and suppressed Akt, NF-κB, Stat3, and Bcl-2 expression more than cucurbitacin D alone. Our results clearly demonstrate that cucurbitacin D could be a useful magazine file storage bins
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WebMonoclonal Antibody for studying Stat1 (Tyr701) phosphate. Cited in 836 publications. Validated for WB, WB, IP, IHC, IF, F, ChIP, ChIP. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-Stat1 (Tyr701) (58D6) Rabbit Monoclonal Antibody (CST #9167) is ready to ship. WebRNA Binding Motif Protein 3 Promotes Cell Metastasis and Epithelial–Mesenchymal Transition Through STAT3 Signaling Pathway in Hepatocellular Carcinoma. Purpose: RNA binding motif protein 3 (RBM3) has been reported to be dysregulated in various cancers and associated with tumor aggressiveness. Epithelial–mesenchymal transition (EMT) is an ... WebMar 2, 2024 · IHC staining showed that the expression of p-STAT3 was correlated with tumor grade, but not other parameters of HNSCC (Fig. 4a; Table 2). Interestingly, the expression levels of GPRC5A and p-STAT3 were inversely correlated, even in different area from the same tumor tissue (Fig. 4 b, c). cottages cardigan