Top2a cancer
Webtop2a PATHOLOGY CERVICAL CANCER BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER … WebAnthracycline is a DNA topoisomerase 2-α (TOP2A) inhibitor and its concomitant over expression with Human Epidermal Growth Factor Receptor 2 (HER2) was investigated of …
Top2a cancer
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WebPred 1 dňom · Anthracycline plus taxane regimens are most efficacious at reducing breast cancer recurrence and death. Regimens with higher cumulative doses of anthracycline plus taxane provide the greatest benefits, challenging the current trend in clinical practice and guidelines towards non-anthracycline chemotherapy, particularly shorter regimens, such … WebPred 1 dňom · Anthracycline plus taxane regimens are most efficacious at reducing breast cancer recurrence and death. Regimens with higher cumulative doses of anthracycline …
Webtop2a PATHOLOGY LIVER CANCER BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER … WebBAZ2A-RNA dependent association with TOP2A and KDM1A represses gene expression in prostate cancer: Organism: Homo sapiens: ... Summary: In this study we show that in prostate cancer, the RNA-binding TAM domain of BAZ2A is required for the repression of Pol II genes that are frequently silenced in the metastatic disease. In contrast to rRNA gene ...
Web28. feb 2024 · In breast cancer, TOP2A expression is closely related to the occurrence and development of tumors and its efficacy on chemotherapy drugs (21,22). It has been noted that the higher the histological grade of breast-invasive ductal carcinoma, the worse the differentiation of tumor cells, and the higher the expression of the TOP2A gene . WebTOP2A. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC.
Web15. jan 2024 · Hepatocellular carcinoma (HCC) is a primary liver cancer with a high mortality rate. However, the molecular mechanism of HCC formation remains to be explored and …
Web21. máj 2024 · Targeting TOP2A is a promising approach in cancer therapy and some agents have been approved in clinical use, such as etoposide and teniposide 18. As an enzyme, ... magnox chapelcross addressWeb12. sep 2003 · To determine the frequency of genomic alterations of HER-2 and TOP2A in bladder cancer, we analyzed the subset of 1,853 tumor samples representing the first … magnox companyWebTOP2A (TOP2) protein expression summary. This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcripti on. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and … magnox cornwallWeb11. sep 2024 · We analyzed the expression profile of TOP2A in various human tumors using Oncomine database, and the results revealed that TOP2A expression was higher in most solid tumors including lung cancer, bladder cancer, brain cancer, breast cancer, digestive tract cancers, liver cancer and many other cancers comparing to their matched normal … magnox control rodsWeb2. nov 2024 · TOP2A is essential for cell division, is highly expressed during mitosis, and is required for mitotic chromosome condensation and segregation ( 13 – 16 ). Genetic … craftsman 47208 innova model numberWeb8. sep 2014 · Our results indicated that TOP2A was the most highly upregulated gene in recurrent/metastatic prostate cancer, and its high expression was positively correlated with poor prognosis in patients. Using a promoter reporter system, we unexpectedly discovered enrichment of CSCs in TOP2Anegcells. craftsman 3000 psi 2.3-gallonWeb15. jan 2024 · Many studies have shown that TOP2A can be a prognostic biomarker and potential therapeutic target for bladder cancer, such as bladder urothelial carcinoma (BLCA), lung adenocarcinoma, prostate cancer, colon cancer and breast cancer [ 12, 13, 14, 15, 16 ]. craftsman 2 panel interior door